Hydrogen Sulfide → 4,6-Dimethylpyrimidin-2-ylthiourea

HRID 579903

Reaktionsgleichung

Reaktionsgleichung von HRID 579903
[C:1]([NH:3][C:4]1[N:9]=[C:8]([CH3:10])[CH:7]=[C:6]([CH3:11])[N:5]=1)#[N:2].[SH2:12].C(Cl)Cl>N1C=CC=CC=1>[CH3:10][C:8]1[CH:7]=[C:6]([CH3:11])[N:5]=[C:4]([NH:3][C:1]([NH2:2])=[S:12])[N:9]=1

Komponenten

5

Edukt 3

HCID 402Hydrogen Sulfide2×HCID 6344DichloromethaneHCID 521618(4,6-Dimethylpyrimidin-2-yl)cyanamide

Produkt 1

HCID 7475004,6-Dimethylpyrimidin-2-ylthiourea

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1049PyridineLösungsmittel

Versuchsvorschrift

A suspension of 10 g of 2-cyanoamino-4,6-dimethylpyrimidine in 50 ml of pyridine was saturated with hydrogen sulfide and stored for 1 hour at 25°. The H2S treatment was repeated twice more, and the mixture was allowed to stir at 25° for 16 hours. Methylene chloride was added, and the product was filtered and washed with methylene chloride to afford 8 g of 4,6-dimethylpyrimidin-2-yl thiourea, m.p. >260°. IR (Nujol) 3280, 3180, 3120, 1610 cm-1.

Aufarbeitung

  1. filtrationthe product was filtered
  2. washwashed with methylene chloride

Quellen und Nachweise

ORD-Eintrag
ord-2917e0a39b774850b396f72ca94bf80d
Quelldatensatz
uspto-grants-1988_06
Patentnummer
US04750930

Verknüpfte Notizen

Wird geladen…