8-Amino-2-naphthalenol → n-(7-Hydroxynaphthalen-1-yl)formamide

HRID 580438Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 580438
[NH2:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:11]=1[CH:10]=[C:9]([OH:12])[CH:8]=[CH:7]2.[C:13](OC(=O)C)(=[O:15])C.C(O)=O>>[CH:13]([NH:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:11]=1[CH:10]=[C:9]([OH:12])[CH:8]=[CH:7]2)=[O:15]

Komponenten

3

Edukt 2

HCID 83588-Amino-2-naphthalenolHCID 19869020Acetic anhydride formic acid

Produkt 1

HCID 244439n-(7-Hydroxynaphthalen-1-yl)formamide

Reaktionsbedingungen

Temperatur
50 °C

Versuchsvorschrift

Ten grams of 8-amino-2-naphthol were added to a mixture of acetic anhydride/formic acid (40 mL:20 mL). The mixture was warmed at 50° C. for one hour and then quenched on ice. After stirring for some time, the product solidified and was filtered off. Recrystallization from ethanol gave 6 g of 8-formamido-2-naphthol melting at 203°-205° C.

Aufarbeitung

  1. customquenched on ice
  2. filtrationwas filtered off
  3. customRecrystallization from ethanol

Quellen und Nachweise

ORD-Eintrag
ord-402682e39859488ca790276b1fbdf26b
Quelldatensatz
uspto-grants-1988_06
Patentnummer
US04753922

Notizen zur Reaktion

Wird geladen…