Sodium Bicarbonate → (R)-4-(2-methyl-6-(3-methylpiperazin-1-yl)pyridin-3-yl)-6-(trifluoromethyl)-1H-indazole

Reaktionsgleichung

Br[C:2]1[CH:3]=[CH:4][C:5]([N:9]2[CH2:14][CH2:13][NH:12][C@H:11]([CH3:15])[CH2:10]2)=[N:6][C:7]=1[CH3:8].[F:16][C:17]([F:31])([F:30])[C:18]1[CH:26]=[C:25]2[C:21]([CH:22]=[N:23][NH:24]2)=[C:20](B(O)O)[CH:19]=1.[C:32]([O-:35])(O)=[O:33].[Na+]>O1CCOCC1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.Cl[Pd]Cl.[Fe+2]>[C:32]([OH:35])([C:17]([F:31])([F:30])[F:16])=[O:33].[CH3:8][C:7]1[C:2]([C:20]2[CH:19]=[C:18]([C:17]([F:31])([F:30])[F:16])[CH:26]=[C:25]3[C:21]=2[CH:22]=[N:23][NH:24]3)=[CH:3][CH:4]=[C:5]([N:9]2[CH2:14][CH2:13][NH:12][C@H:11]([CH3:15])[CH2:10]2)[N:6]=1