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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 581287Erstellt: 25. Oktober 2026

3-Thenoyl chloride → 5-(N-[3-thiophenecarbonyl]amino)-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridine

https://huagongshe.com/reaction/581287

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt3-Thenoyl chlorideHCID 2776377—
Edukt3-(1-Methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]pyridin-5-ylamineHCID 10220230—
Produkt5-(N-[3-thiophenecarbonyl]amino)-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridineHCID 1104608764,2%

Reaktionsschritte

Beginning with 1.5 gm (6.5 mMol) 5-amino-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridine and 1.2 gm (7.8 mMol) 3-thiophenecarbonyl chloride, 1.42 gm (64%) of the title compound were prepared essentially by the procedure described in Example 4.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05919936
Quelldatensatzuspto-grants-1999_07
ORD IDord-d1596f6dac194c899a1ad73a09e7beb0
Quellennotizuspto-grants-1999_07