HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
5-Methylthiophene-2-carbonyl chloride → 5-(N-[5-methyl-2-thiophenecarbonyl]amino)-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 5-Methylthiophene-2-carbonyl chloride | HCID 2760083 | — |
| Edukt | 3-(1-Methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]pyridin-5-ylamine | HCID 10220230 | — |
| Produkt | 5-(N-[5-methyl-2-thiophenecarbonyl]amino)-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridine | HCID 19601511 | 86% |
Reaktionsschritte
Beginning with 0.40 gm (1.74 mMol) 5-amino-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridine and 0.34 gm (2.08 mMol) 5-methyl-2-thiophenecarbonyl chloride, 0.53 gm (86%) of the title compound were prepared essentially by the procedure described in Example 4.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05919936 |
| Quelldatensatz | uspto-grants-1999_07 |
| ORD ID | ord-a44ee4fe638d44faa7d216bfacd7dea7 |
| Quellennotiz | uspto-grants-1999_07 |