6-(3,5-Dimethyl-benzoyl)-5-isopropyl-1H-pyrimidine-2,4-dione → 1-[2-(Cyclopent-3-en-1-yl)ethyl]-5-isopropyl-6-(3,5-dimethylbenzoyl)-2,4-pyrimidinedione

HRID 581882

Reaktionsgleichung

Reaktionsgleichung von HRID 581882
[CH:1]([C:4]1[C:5](=[O:21])[NH:6][C:7](=[O:20])[NH:8][C:9]=1[C:10](=[O:19])[C:11]1[CH:16]=[C:15]([CH3:17])[CH:14]=[C:13]([CH3:18])[CH:12]=1)([CH3:3])[CH3:2].C1(C)C(S(O[CH2:32][CH2:33][CH:34]2[CH2:38][CH:37]=[CH:36][CH2:35]2)(=O)=O)=CC=CC=1>>[CH:34]1([CH2:33][CH2:32][N:8]2[C:9]([C:10](=[O:19])[C:11]3[CH:12]=[C:13]([CH3:18])[CH:14]=[C:15]([CH3:17])[CH:16]=3)=[C:4]([CH:1]([CH3:3])[CH3:2])[C:5](=[O:21])[NH:6][C:7]2=[O:20])[CH2:38][CH:37]=[CH:36][CH2:35]1

Komponenten

3

Edukt 2

HCID 222565826-(3,5-Dimethyl-benzoyl)-5-isopropyl-1H-pyrimidine-2,4-dioneHCID 867542212-(Cyclopent-3-en-1-yl)ethyl toluenesulfonate

Produkt 1

HCID 4746081-[2-(Cyclopent-3-en-1-yl)ethyl]-5-isopropyl-6-(3,5-dimethylbenzoyl)-2,4-pyrimidinedioneAusbeute 36,8 %

Versuchsvorschrift

5-Isopropyl-6-(3,5-dimethylbenzoyl)-2,4-pyrimidinedione and 2-(cyclopent-3-en-1-yl)ethyl toluenesulfonate were reacted by the same method with example 35 to obtain the titled compound (140 mg).

Quellen und Nachweise

ORD-Eintrag
ord-85a01cef7d7f4a3e8f6d894eb6e41671
Quelldatensatz
uspto-grants-1999_07
Patentnummer
US05922727

Verknüpfte Notizen

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