Trifluoroacetic acid → 4-(Carboxymethyloxy)-4'-cyano-biphenyl

HRID 582147

Reaktionsgleichung

Reaktionsgleichung von HRID 582147
C([O:5][C:6]([CH2:8][O:9][C:10]1[CH:15]=[CH:14][C:13]([C:16]2[CH:21]=[CH:20][C:19]([C:22]#[N:23])=[CH:18][CH:17]=2)=[CH:12][CH:11]=1)=[O:7])(C)(C)C.FC(F)(F)C(O)=O>C(Cl)Cl>[C:6]([CH2:8][O:9][C:10]1[CH:11]=[CH:12][C:13]([C:16]2[CH:21]=[CH:20][C:19]([C:22]#[N:23])=[CH:18][CH:17]=2)=[CH:14][CH:15]=1)([OH:7])=[O:5]

Komponenten

4

Edukt 2

HCID 6422Trifluoroacetic acidHCID 640094Tert-butyl [(4'-cyanobiphenyl-4-yl)oxy]acetate

Produkt 1

HCID 432431004-(Carboxymethyloxy)-4'-cyano-biphenyl

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

32.9 g of 4-(tert.butyloxycarbonylmethyloxy)-4'-cyano-biphenyl dissolved in 250 ml of methylene chloride is mixed slowly with 137 ml of trifluoroacetic acid. After stirring for 3 hours, the reaction mixture is evaporated to dryness and the solid residue is triturated with water.

Aufarbeitung

  1. customthe reaction mixture is evaporated to dryness
  2. customthe solid residue is triturated with water

Quellen und Nachweise

ORD-Eintrag
ord-4d9ef553cb9c45fc9547898ae79c4bce
Quelldatensatz
uspto-grants-1999_07
Patentnummer
US05922763

Verknüpfte Notizen

Wird geladen…