Ethanol → HCID 53793766, Verbindung

HRID 582272

Reaktionsgleichung

Reaktionsgleichung von HRID 582272
[C:1]([O:5]CC)(=O)[CH:2]=[CH2:3].[Cl:8][C:9]1[CH:14]=[C:13]([Cl:15])[CH:12]=[CH:11][C:10]=1[NH:16][NH2:17].[O-]CC.[Na+].C(O)C>C1(C)C=CC=CC=1>[Cl:8][C:9]1[CH:14]=[C:13]([Cl:15])[CH:12]=[CH:11][C:10]=1[N:16]1[CH2:3][CH2:2][C:1](=[O:5])[NH:17]1

Komponenten

6

Edukt 4

HCID 702EthanolHCID 8821Ethyl AcrylateHCID 408929(2,4-Dichlorophenyl)hydrazineHCID 2723922Sodium ethoxide

Produkt 1

HCID 53793766HCID 53793766, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Versuchsvorschrift

105.0 g (1.05 mol) of ethyl acrylate is added dropwise to a mixture of 37.3 g (211 mmol) of 2,4-dichlorophenylhydrazine, 18.6 g (273 mmol) of sodium ethoxide, 150 ml of ethanol and 150 ml of toluene and the mixture is subsequently stirred for 1 hour. The reaction mixture is evaporated to 100 ml and the residue is taken up in water. The organic phase is separated off and extracted with 5% strength NaOH. The combined aqueous phases are adjusted to a pH of 6.5 and the solid formed is filtered off with suction, washed with water and dried under reduced pressure.

Aufarbeitung

  1. customThe reaction mixture is evaporated to 100 ml
  2. customThe organic phase is separated off
  3. extractionextracted with 5% strength NaOH
  4. customthe solid formed
  5. filtrationis filtered off with suction
  6. washwashed with water
  7. customdried under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-34b2a9f17ced415e99b406e2c111f7af
Quelldatensatz
uspto-grants-1999_07
Patentnummer
US05922886

Verknüpfte Notizen

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