3-(2-(2-(2-(Trifluoromethoxy)tetrafluoroethoxy)tetrafluoroethoxy)-2,2-difluoroethoxy)propyl chloride → 2-Octyloxy-7-(3-(2-(2-(2-(trifluoromethoxy)tetrafluoroethoxy)tetrafluoroethoxy)-2,2-difluoroethoxy)propoxy)fluorene

HRID 582996Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 582996
[CH2:1]([O:9][C:10]1[CH:22]=[CH:21][C:20]2[C:19]3[C:14](=[CH:15][C:16]([OH:23])=[CH:17][CH:18]=3)[CH2:13][C:12]=2[CH:11]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[F:24][C:25]([F:51])([F:50])[O:26][C:27]([F:49])([F:48])[C:28]([F:47])([F:46])[O:29][C:30]([F:45])([F:44])[C:31]([F:43])([F:42])[O:32][C:33]([F:41])([F:40])[CH2:34][O:35][CH2:36][CH2:37][CH2:38]Cl.FC(F)(F)OC(F)(F)C(F)(F)OC(F)(F)C(F)(F)OC(F)(F)COCCCBr>>[CH2:1]([O:9][C:10]1[CH:22]=[CH:21][C:20]2[C:19]3[C:14](=[CH:15][C:16]([O:23][CH2:38][CH2:37][CH2:36][O:35][CH2:34][C:33]([O:32][C:31]([F:42])([F:43])[C:30]([F:44])([F:45])[O:29][C:28]([F:46])([F:47])[C:27]([F:48])([F:49])[O:26][C:25]([F:51])([F:50])[F:24])([F:41])[F:40])=[CH:17][CH:18]=3)[CH2:13][C:12]=2[CH:11]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

Komponenten

4

Edukt 3

HCID 212252903-(2-(2-(2-(Trifluoromethoxy)tetrafluoroethoxy)tetrafluoroethoxy)-2,2-difluoroethoxy)propyl chlorideHCID 212253953-(2-(2-(2-(Trifluoromethoxy)tetrafluoroethoxy)tetrafluoroethoxy)-2,2-difluoroethoxy)propyl bromideHCID 218324622-Octyloxy-7-hydroxyfluorene

Produkt 1

HCID 212253882-Octyloxy-7-(3-(2-(2-(2-(trifluoromethoxy)tetrafluoroethoxy)tetrafluoroethoxy)-2,2-difluoroethoxy)propoxy)fluorene

Versuchsvorschrift

The title compound was prepared essentially as in Example 1 by combining 2-octyloxy-7-hydroxyfluorene (1.0 g, 3.2 mmol) with a mixture of 3-(2-(2-(2-(trifluoromethoxy)tetrafluoroethoxy)tetrafluoroethoxy)-2,2-difluoroethoxy)propyl chloride and 3-(2-(2-(2-(trifluoromethoxy)tetrafluoroethoxy)tetrafluoroethoxy)-2,2-difluoroethoxy)propyl bromide (total 1.62 g, 3.3 mmol, 80:20 mole ratio). The reaction mixture was quenched by addition of water, and the resulting crude product was recrystallized from ethanol and further purified by Kugelrohr distillation (188° C. at 0.01 torr) to provide a yield of 0.84 g.

Aufarbeitung

  1. customThe reaction mixture was quenched by addition of water
  2. customthe resulting crude product was recrystallized from ethanol
  3. distillationfurther purified by Kugelrohr distillation (188° C. at 0.01 torr)
  4. customto provide a yield of 0.84 g

Quellen und Nachweise

ORD-Eintrag
ord-40f70ba16887488aaec23fbd3dbdc9e5
Quelldatensatz
uspto-grants-1999_07
Patentnummer
US05928562

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