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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 584124Erstellt: 25. Oktober 2026

Succinic anhydride → 3-[3-(4-Methylsulfanyl-phenyl)-[1,2,4]oxadiazol-5-yl]-propionic acid

https://huagongshe.com/reaction/584124

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktSuccinic anhydrideHCID 7922—
EduktHCID 178503197HCID 178503197—
LösungsmittelDimethylformamideHCID 6228—
Produkt3-[3-(4-Methylsulfanyl-phenyl)-[1,2,4]oxadiazol-5-yl]-propionic acidHCID 17122273—

Reaktionsbedingungen

Temperatur120 °C

Reaktionsschritte

Succinic anhydride (112 mg, 1.12 mmol) and N-hydroxy-4-methylsulfanyl-benzamidine (203 mg, 1.12 mmol) were dissolved in 2.0 mL of DMF and heated at 120° C. overnight. The cooled solution was evaporated and dried to give 3-[3-(4-methylsulfanyl-phenyl)-[1,2,4]oxadiazol-5-yl]-propionic acid which was used without further purification.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06924284B2
Quelldatensatzuspto-grants-2005_08
ORD IDord-1c92a610d92b49ddaf94ad9316aee7bc
Quellennotizuspto-grants-2005_08