2-Chloroethyl methyl ether → 1-Bromo-2-ethyl-5-ethoxymethoxybenzene
Reaktionsgleichung
[Br:1][C:2]1[CH:3]=[C:4]([OH:10])[CH:5]=[CH:6][C:7]=1[CH2:8][CH3:9].[CH3:11][O:12][CH2:13][CH2:14]Cl>>[Br:1][C:2]1[CH:3]=[C:4]([O:10][CH2:11][O:12][CH2:13][CH3:14])[CH:5]=[CH:6][C:7]=1[CH2:8][CH3:9]Komponenten
3
Versuchsvorschrift
In a manner similar to that of Example 1(e), by reacting 13 g (65 mmol) of 3-bromo-4-ethylphenol with 6.7 ml (72 mmol) of methoxyethyl chloride, and after purification by chromatography on a column of silica eluted with a mixture of heptane and ethyl acetate (90/10), 12 g (76%) of the expected product are obtained in the form of a yellow oil.
Aufarbeitung
- customafter purification by chromatography on a column of silica
- washeluted with a mixture of heptane and ethyl acetate (90/10), 12 g (76%) of the expected product
- customare obtained in the form of a yellow oil
Quellen und Nachweise
- ORD-Eintrag
- ord-4c73d5adae1e4cc19265abee89b64b8f
- Quelldatensatz
- uspto-grants-2005_08
- Patentnummer
- US06924400B2
Notizen zur Reaktion
Wird geladen…