2-Chloro-6-ethoxyquinoline-3-carbaldehyde → 2-Chloro-6-ethoxyquinoline-3-carbaldehyde-O-methyl-oxime

HRID 584665Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 584665
[Cl:1][C:2]1[C:11]([CH:12]=O)=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([O:14][CH2:15][CH3:16])[CH:8]=2)[N:3]=1.Cl.[CH3:18][O:19][NH2:20].C(O)C>>[CH3:18][O:19][N:20]=[CH:12][C:11]1[C:2]([Cl:1])=[N:3][C:4]2[C:9]([CH:10]=1)=[CH:8][C:7]([O:14][CH2:15][CH3:16])=[CH:6][CH:5]=2

Komponenten

3

Edukt 2

HCID 7886582-Chloro-6-ethoxyquinoline-3-carbaldehydeHCID 22341071HCID 22341071, Verbindung

Produkt 1

HCID 738840702-Chloro-6-ethoxyquinoline-3-carbaldehyde-O-methyl-oxime

Versuchsvorschrift

To a solution of 2-chloro-6-ethoxyquinoline-3-carbaldehyde (0.235 g, 1.0 mmol) in ethanol O-methylhydroxylamine hydrochloride (0.10 g, 1.1 mmol) was added. The reaction mixture was heated to reflux for 0.5 hours. After cooling to room temperature the precipitated compound was filtered and dried. Yield 180 mg. M.p. 142-4° C.

Aufarbeitung

  1. temperatureThe reaction mixture was heated
  2. temperatureto reflux for 0.5 hours
  3. filtrationwas filtered
  4. customdried

Quellen und Nachweise

ORD-Eintrag
ord-a54f64eba8e247f0ae17a36478d376c7
Quelldatensatz
uspto-grants-2005_08
Patentnummer
US06927214B1

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