O-Methyl-L-Tyrosine → (S)-2-(Biphenyl-3-ylamino)-3-(4-methoxy-phenyl)-propionic acid
Reaktionsgleichung
[C:1]1([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[CH:6]=[CH:5][CH:4]=[C:3]([NH:7][C@@H:8]([CH2:12][C:13]2[CH:18]=[C:17](OC)[C:16]([O:21][CH3:22])=[C:15](OC)[CH:14]=2)[C:9]([OH:11])=[O:10])[CH:2]=1.COC1C=CC(C[C@@H](C(O)=O)N)=CC=1>>[C:1]1([C:25]2[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=2)[CH:6]=[CH:5][CH:4]=[C:3]([NH:7][C@@H:8]([CH2:12][C:13]2[CH:18]=[CH:17][C:16]([O:21][CH3:22])=[CH:15][CH:14]=2)[C:9]([OH:11])=[O:10])[CH:2]=1Komponenten
3
Versuchsvorschrift
The title compound is prepared as described for (S)-2-(Biphenyl-3-ylamino)-3-(3,4,5-trimethoxy-phenyl)-propionic acid (example 1) but using O-methyl-L-tyrosine (Bachem).
Quellen und Nachweise
- ORD-Eintrag
- ord-ae0bc738f60a43cc8585e18f6c6b41bd
- Quelldatensatz
- uspto-grants-2005_08