HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Chloroaniline → 1-(3-Chlorophenyl)-2-oxo-3-pyrrolidinecarboxylic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Chloroaniline | HCID 7932 | — |
| Edukt | 6,6-Dimethyl-5,7-dioxaspiro(2.5)octane-4,8-dione | HCID 79720 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 1-(3-Chlorophenyl)-2-oxo-3-pyrrolidinecarboxylic acid | HCID 4122939 | 81,2% |
Reaktionsschritte
This compound was prepared according to general method 1 starting from 6,6-dimethyl-5,7-dioxaspiro[2.5]octane-4,8-dione (0.250 g; 1.45 mmol) and 3-chloroaniline (0.469 mL; 4.36 mmol) in ethanol (3 mL). 1-(3-chlorophenyl)-2-oxopyrrolidine-3-carboxylic acid 0.282 g (81%) was obtained as a solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09434722B2 |
| Quelldatensatz | uspto-grants-2016_09 |
| ORD ID | ord-0c4490ca144c4b4cb8876a27568a9f34 |
| Quellennotiz | uspto-grants-2016_09 |