HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
6,6-Dimethyl-5,7-dioxaspiro(2.5)octane-4,8-dione → 1-(2,3-dihydro-1H-inden-5-yl)-2-oxopyrrolidine-3-carboxylic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 6,6-Dimethyl-5,7-dioxaspiro(2.5)octane-4,8-dione | HCID 79720 | — |
| Edukt | Indan-5-amine | HCID 90496 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 1-(2,3-dihydro-1H-inden-5-yl)-2-oxopyrrolidine-3-carboxylic acid | HCID 24688697 | 71,7% |
Reaktionsschritte
This compound was prepared according to general method 1 starting from 6,6-dimethyl-5,7-dioxaspiro[2.5]octane-4,8-dione (0.250 g; 1.45 mmol) and 2,3-dihydro-1H-inden-5-amine (0.593 g; 4.36 mmol) in ethanol (3 mL). 1-(2,3-dihydro-1H-inden-5-yl)-2-oxopyrrolidine-3-carboxylic acid 0.255 g (71%) was obtained as a white solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09434722B2 |
| Quelldatensatz | uspto-grants-2016_09 |
| ORD ID | ord-dd8884cb3ecb43a8ae271bc771ede609 |
| Quellennotiz | uspto-grants-2016_09 |