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HRID 585952Erstellt: 25. Oktober 2026

2,4-Dichlorophenethylamine → N-[2-(2,4-dichlorophenyl)ethyl]-N'-1H-indol-4-ylurea

https://huagongshe.com/reaction/585952

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt2,4-DichlorophenethylamineHCID 142938—
Edukt4-isocyanato-1H-indoleHCID 22032644—
ProduktN-[2-(2,4-dichlorophenyl)ethyl]-N'-1H-indol-4-ylureaHCID 9975018—

Reaktionsschritte

2-(2,4-Dichlorophenyl)ethylamine (0.21 g, 1.1 mmol) and the product of Example 80A (0.16 g, 1. mmol) were treated as described in Example 80B to provide the title compound. mp 170° C.; 1H NMR (300 MHz, DMSO-d6) δ 2.90 (m, 2H), 3.31 (m, 2H), 6.47 (m, 2H), 6.93 (m, 2H), 7.23 (m, 1H), 7.40 (m, 2H), 7.60 (m, 2H), 8.15 (s, 1H), 11.02 (s, 1H). MS (DCI+) m/z 347 (M+H). Anal. Calcd. for C17H15N3Cl20: C, 58.63; H, 4.34; N, 12.07. Found: C, 58.49; H, 4.49; N, 12.38.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06933311B2
Quelldatensatzuspto-grants-2005_08
ORD IDord-f0e02111fadd487abf37f38ced233cc6
Quellennotizuspto-grants-2005_08