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HRID 585967Erstellt: 25. Oktober 2026

1H-Indazol-4-amine, 1-methyl- → N-[4-(1-azepanyl)benzyl]-N'-(1-methyl-1H-indazol-4-yl)urea

https://huagongshe.com/reaction/585967

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt1H-Indazol-4-amine, 1-methyl-HCID 153838—
EduktNoName_3327HCID 413085—
Edukt1-[4-(Isocyanatomethyl)phenyl]azepaneHCID 22337702—
ProduktN-[4-(1-azepanyl)benzyl]-N'-(1-methyl-1H-indazol-4-yl)ureaHCID 22337694—

Reaktionsschritte

The title compound was prepared using the procedure described in Example 89B using 1-[4-(isocyanatomethyl)phenyl]azepane and 1-methyl-1H-indazol-4-amine instead of 1-bromo-4-(isocyanatomethyl)benzene and the product from Example 89A. NMR (DMSO-d6) δ 8.97 (s, 1H), 8.18 (s, 1H), 7.65 (d, 1H), 7.14 (m, 4H), 7.11 (d, 1H), 6.95 (bs, 2H), 4.23 (s, 2H), 3.99 (s, 3H), 3.27 (m, 4H), 1.90 (m, 4H), 1.53 (m, 4H); MS (ESI) (M+H)+ 378.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06933311B2
Quelldatensatzuspto-grants-2005_08
ORD IDord-d35ea2aeebdf456d9fbb49d8a29f9115
Quellennotizuspto-grants-2005_08