3,3,4-Trimethylpentan-1-ol → 3,3,4-Trimethylpentanal

HRID 586142Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 586142
[CH3:1][C:2]([CH3:9])([CH:6]([CH3:8])[CH3:7])[CH2:3][CH2:4][OH:5].[Cr](Cl)([O-])(=O)=O.[NH+]1C=CC=CC=1>C(Cl)Cl>[CH3:1][C:2]([CH3:9])([CH:6]([CH3:8])[CH3:7])[CH2:3][CH:4]=[O:5]

Komponenten

4

Edukt 2

HCID 124253343,3,4-Trimethylpentan-1-olHCID 178418287HCID 178418287, Verbindung

Produkt 1

HCID 124253353,3,4-Trimethylpentanal

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

3,3,4-Trimethylpentanol (1 equiv) is dissolved in CH2Cl2. Pyridinium chlorochromate (1.5 equiv) is added and the resulting mixture is stirred at ambient temperature. The liquid is decanted and concentrated by rotary evaporation. The residue is triturated with 1 to 1 diethyl ether/hexane and mixture is filtered and the filtrate is washed with 1 N HCl. The organic layer is dried over Na2SO4, decanted and concentrated. The aldehyde is purified by fractional distillation to yield 3,3,4-trimethylpentanal.

Aufarbeitung

  1. customThe liquid is decanted
  2. concentrationconcentrated by rotary evaporation
  3. customThe residue is triturated with 1 to 1 diethyl ether/hexane and mixture
  4. filtrationis filtered
  5. washthe filtrate is washed with 1 N HCl
  6. dry with materialThe organic layer is dried over Na2SO4
  7. customdecanted
  8. concentrationconcentrated
  9. distillationThe aldehyde is purified by fractional distillation

Quellen und Nachweise

ORD-Eintrag
ord-c4d859fffe7a41c28f5913316149751e
Quelldatensatz
uspto-grants-2005_08
Patentnummer
US06936606B2

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