Methyl 2-{[(benzyloxy)carbonyl]amino}-2-(dimethyl phosphono)acetate → 2-Benzyloxycarbonylamino-5,5,6-trimethyl-heptanoic acid
Reaktionsgleichung
[CH3:1][C:2]([CH3:9])([CH:6]([CH3:8])[CH3:7])[CH2:3][CH:4]=O.C[O:11][C:12]([CH:14](P(OC)(OC)=O)[NH:15][C:16]([O:18][CH2:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)=[O:17])=[O:13]>>[CH2:19]([O:18][C:16]([NH:15][CH:14]([CH2:4][CH2:3][C:2]([CH3:9])([CH3:1])[CH:6]([CH3:8])[CH3:7])[C:12]([OH:13])=[O:11])=[O:17])[C:20]1[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=1Komponenten
3
Versuchsvorschrift
This aldehyde may be converted to the title compound by reaction with N-(Benzyloxycarbonyl)-α-phosphonoglycine trimethyl ester, followed by catalytic reduction and hydrolysis by the procedures described in Example 4.
Quellen und Nachweise
- ORD-Eintrag
- ord-03ff5798901e4c71990024c28b3550d5
- Quelldatensatz
- uspto-grants-2005_08