HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-(Methoxymethyl)piperidine hydrochloride → rac-3-[(4-(2-Methoxymethylpiperidin-1-yl)-1,3,5-triazin-2-yl)amino]-benzenemethanesulfonamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-(Methoxymethyl)piperidine hydrochloride | HCID 45926159 | — |
| Edukt | 3-[(4-(4,4-Difluoropiperidin-1-yl)-1,3,5-triazin-2-yl)amino]-benzenemethanesulfonamide | HCID 60197102 | — |
| Edukt | 3-[(4-Chloro-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide | HCID 86679822 | — |
| Produkt | rac-3-[(4-(2-Methoxymethylpiperidin-1-yl)-1,3,5-triazin-2-yl)amino]-benzenemethanesulfonamide | HCID 60197106 | — |
Reaktionsschritte
B4 was prepared following the procedure reported for B2 using A1 and rac-2-methoxymethylpiperidine hydrochloride. The title compound was purified by thick-layer chromatography (silica gel, chloroform/MeOH 19:1) and obtained as a white crystalline solid; yield: 235 mg (67%). MS (ES) C17H24N6O3S requires: 392. found: 393 (M+H)+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09226929B2 |
| Quelldatensatz | uspto-grants-2016_01 |
| ORD ID | ord-db7379088f3d4dcca8d5b74f80ebf560 |
| Quellennotiz | uspto-grants-2016_01 |