Dimethyl-(2-piperidin-2-yl-ethyl)-amine → rac-3-[(4-(2-(2-(Dimethylamino)ethyl)piperidin-1-yl)-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide
Reaktionsgleichung
CO[CH2:3][CH:4]1[CH2:9][CH2:8][CH2:7][CH2:6][N:5]1[C:10]1[N:15]=[CH:14][N:13]=[C:12]([NH:16][C:17]2[CH:18]=[C:19]([CH2:23][S:24]([NH2:27])(=[O:26])=[O:25])[CH:20]=[CH:21][CH:22]=2)[N:11]=1.ClC1N=CN=C(NC2C=C(CS(N)(=O)=O)C=CC=2)N=1.[CH3:47][N:48]([CH3:57])[CH2:49]CC1CCCCN1>>[CH3:47][N:48]([CH3:57])[CH2:49][CH2:3][CH:4]1[CH2:9][CH2:8][CH2:7][CH2:6][N:5]1[C:10]1[N:15]=[CH:14][N:13]=[C:12]([NH:16][C:17]2[CH:18]=[C:19]([CH2:23][S:24]([NH2:27])(=[O:26])=[O:25])[CH:20]=[CH:21][CH:22]=2)[N:11]=1Komponenten
4
Edukt 3
Produkt 1
Versuchsvorschrift
B8 was prepared following the procedure reported for B4 using A1 and rac-2-(2-(dimethylamino)ethyl)piperidine and obtained as a white crystalline solid; yield: 230 mg (61%). MS (ES) C19H29N7O2S requires: 419. found: 420 (M+H)+.