(6-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-yl)-dimethyl-amine → (2-Dimethylamino-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-carbamic acid tert-butyl ester

HRID 588441

Reaktionsgleichung

Reaktionsgleichung von HRID 588441
BrC1C=CC2N(N=C(N(C)C)N=2)C=1.[C:14]([O:18][C:19](=[O:36])[NH:20][C:21]1[CH:22]=[CH:23][C:24]2[N:25]([N:27]=[C:28]([N:30]3[CH2:35]COC[CH2:31]3)[N:29]=2)[CH:26]=1)([CH3:17])([CH3:16])[CH3:15]>>[C:14]([O:18][C:19](=[O:36])[NH:20][C:21]1[CH:22]=[CH:23][C:24]2[N:25]([N:27]=[C:28]([N:30]([CH3:31])[CH3:35])[N:29]=2)[CH:26]=1)([CH3:17])([CH3:16])[CH3:15]

Komponenten

3

Edukt 2

HCID 89464315(6-Bromo-[1,2,4]triazolo[1,5-a]pyridin-2-yl)-dimethyl-amineHCID 89464434Tert-butyl 2-morpholin-4-yl-[1,2,4]triazolo[1,5-a]pyridin-6-ylcarbamate

Produkt 1

HCID 89464594(2-Dimethylamino-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-carbamic acid tert-butyl ester

Versuchsvorschrift

Using (6-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-yl)-dimethyl-amine, this compound was prepared following the same method as for the synthesis of (2-morpholin-4-yl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-carbamic acid tert-butyl ester. Reddish yellow solid (250 mg, 33%). MS: m/z=278 (M+H+).

Aufarbeitung

  1. customthis compound was prepared

Quellen und Nachweise

ORD-Eintrag
ord-4e6dd002aa6d47028d39db456bbb1111
Quelldatensatz
uspto-grants-2016_01
Patentnummer
US09227970B2

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