5-(2-Dimethylamino-[1,2,4]triazolo[1,5-a]pyridin-6-ylcarbamoyl)-1-methyl-1H-pyrazole-4-carboxylic acid ethyl ester → HCID 89464053, Verbindung

HRID 588444

Reaktionsgleichung

Reaktionsgleichung von HRID 588444
C([O:3][C:4]([C:6]1[CH:7]=[N:8][N:9]([CH3:26])[C:10]=1[C:11](=[O:25])[NH:12][C:13]1[CH:14]=[CH:15][C:16]2[N:17]([N:19]=[C:20]([N:22]([CH3:24])[CH3:23])[N:21]=2)[CH:18]=1)=[O:5])C.CN1C(C(=O)NC2C=CC3N(N=C(N4CCOCC4)N=3)C=2)=C(C(O)=O)C=N1>>[CH3:23][N:22]([CH3:24])[C:20]1[N:21]=[C:16]2[CH:15]=[CH:14][C:13]([NH:12][C:11]([C:10]3[N:9]([CH3:26])[N:8]=[CH:7][C:6]=3[C:4]([OH:5])=[O:3])=[O:25])=[CH:18][N:17]2[N:19]=1

Komponenten

3

Edukt 2

HCID 894638695-(2-Dimethylamino-[1,2,4]triazolo[1,5-a]pyridin-6-ylcarbamoyl)-1-methyl-1H-pyrazole-4-carboxylic acid ethyl esterHCID 894643091-Methyl-5-(2-morpholino-[1,2,4]triazolo[1,5-a]pyridin-6-ylcarbamoyl)-1H-pyrazole-4-carboxylic acid

Produkt 1

HCID 89464053HCID 89464053, Verbindung

Versuchsvorschrift

Using 5-(2-dimethylamino-[1,2,4]triazolo[1,5-a]pyridin-6-ylcarbamoyl)-1-methyl-1H-pyrazole-4-carboxylic acid ethyl ester, this compound was prepared following the same method as for the synthesis of 1-Methyl-5-(2-morpholino-[1,2,4]triazolo[1,5-a]pyridin-6-ylcarbamoyl)-1H-pyrazole-4-carboxylic acid. Brown solid (41 mg, 70%). MS: m/z=330 (M+H+).

Aufarbeitung

  1. customthis compound was prepared

Quellen und Nachweise

ORD-Eintrag
ord-11f8bda3a7074117a8d08b9f7258c127
Quelldatensatz
uspto-grants-2016_01
Patentnummer
US09227970B2

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