Oxalyl chloride → 2-Chloro-6-fluorobenzoyl isocyanate

Beteiligte Stoffe

Reaktionsschritte

To a solution of 2-chloro-6-fluorobenzamide (2.0 g, 0.011 mmol) in EDC (10 mL) was added oxalyl chloride (2.18 g, 0.017 mmol). The reaction mass was refluxed for 24 h. Excess of solvent was removed under vacuum to afford 2.0 g of desired product.

Herkunft & Nachweise