HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Ammonia → 3-((2,2,2-Trifluoroacetamido)methyl)-2,6-dimethylbenzamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Ammonia | HCID 222 | — |
| Edukt | Oxalyl chloride | HCID 65578 | — |
| Edukt | 2,6-Dimethyl-3-((2,2,2-trifluoroacetamido)methyl)benzoic acid | HCID 86692227 | — |
| Lösungsmittel | Tetrahydrofuran | HCID 8028 | — |
| Produkt | 3-((2,2,2-Trifluoroacetamido)methyl)-2,6-dimethylbenzamide | HCID 90019133 | — |
Reaktionsschritte
The title compound was prepared according to the procedure described in step-2 of Intermediate-26 by using 3-((2,2,2-trifluoroacetamido)methyl)-2,6-dimethylbenzoic acid (1.0 g), oxalyl chloride (1.0 mL), THF (50 mL) and ammonia gas to afford 0.800 g of the desired product.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09439890B2 |
| Quelldatensatz | uspto-grants-2016_09 |
| ORD ID | ord-af0e292915e14969a20ac42f8ad78e43 |
| Quellennotiz | uspto-grants-2016_09 |