HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Sulfuric Acid → N-(5-amino-4-chloro-2-fluorobenzyl)-2,2,2-trifluoroacetamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Sulfuric Acid | HCID 1118 | — |
| Edukt | Sodium Azide | HCID 33557 | — |
| Edukt | 5-((2,2,2-Trifluoroacetamido)methyl)-2-chloro-4-fluorobenzoic acid | HCID 89736668 | — |
| Produkt | N-(5-amino-4-chloro-2-fluorobenzyl)-2,2,2-trifluoroacetamide | HCID 90018998 | 64.668,398% |
Reaktionsschritte
The title compound was prepared according to the procedure described in step-1 of Intermediate-57 by using 5-((2,2,2-trifluoroacetamido)methyl)-2-chloro-4-fluorobenzoic acid (3.0 g), conc. H2SO4 and sodium azide (0.793 g, 0.012 mmol) to afford 2.1 g of the desired product.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09439890B2 |
| Quelldatensatz | uspto-grants-2016_09 |
| ORD ID | ord-069b0936d7534524b20bdb7e804dfc9b |
| Quellennotiz | uspto-grants-2016_09 |