HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Quinolinecarboxaldehyde → 6-(2,6-Dimethoxyphenyl)-1-(quinolin-2-ylmethyl)piperidin-2-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Quinolinecarboxaldehyde | HCID 79619 | — |
| Edukt | Methyl 5-amino-5-(2,6-dimethoxyphenyl)pentanoate | HCID 69082713 | — |
| Produkt | 6-(2,6-Dimethoxyphenyl)-1-(quinolin-2-ylmethyl)piperidin-2-one | HCID 69081964 | — |
Reaktionsschritte
Prepared according to the described general procedure 1 (GP1) by reaction of methyl 5-amino-5-(2,6-dimethoxyphenyl)pentanoate with commercially available quinoline-2-carbaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.59 min.; [M+H]+: 377.18 g/mol.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09242970B2 |
| Quelldatensatz | uspto-grants-2016_01 |
| ORD ID | ord-8ab9b6d57eaa4caca7f022940d5721a0 |
| Quellennotiz | uspto-grants-2016_01 |