HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Quinoxaline-6-carboxaldehyde → 6-(2,6-Dimethoxyphenyl)-1-(quinoxalin-6-ylmethyl)piperidin-2-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Quinoxaline-6-carboxaldehyde | HCID 763958 | — |
| Edukt | Methyl 5-amino-5-(2,6-dimethoxyphenyl)pentanoate | HCID 69082713 | — |
| Produkt | 6-(2,6-Dimethoxyphenyl)-1-(quinoxalin-6-ylmethyl)piperidin-2-one | HCID 69083291 | — |
Reaktionsschritte
Prepared according to the described general procedure 1 (GP1) by reaction of methyl 5-amino-5-(2,6-dimethoxyphenyl)pentanoate with commercially available quinoxaline-6-carbaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.68 min.; [M+H]+: 378.17 g/mol.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09242970B2 |
| Quelldatensatz | uspto-grants-2016_01 |
| ORD ID | ord-473aa4eb336943609ea42eb15e4144c1 |
| Quellennotiz | uspto-grants-2016_01 |