2-Methyl-1,3-benzothiazole-6-carbaldehyde → 6-(2,4-Dimethoxypyridin-3-yl)-1-((2-methylbenzo[d]thiazol-6-yl)methyl)piperidin-2-one
Reaktionsgleichung
[NH2:1][CH:2]([C:10]1[C:11]([O:18][CH3:19])=[N:12][CH:13]=[CH:14][C:15]=1[O:16][CH3:17])[CH2:3][CH2:4][CH2:5][C:6]([O:8]C)=O.[CH3:20][C:21]1[S:22][C:23]2[CH:29]=[C:28]([CH:30]=O)[CH:27]=[CH:26][C:24]=2[N:25]=1>>[CH3:19][O:18][C:11]1[C:10]([CH:2]2[N:1]([CH2:30][C:28]3[CH:27]=[CH:26][C:24]4[N:25]=[C:21]([CH3:20])[S:22][C:23]=4[CH:29]=3)[C:6](=[O:8])[CH2:5][CH2:4][CH2:3]2)=[C:15]([O:16][CH3:17])[CH:14]=[CH:13][N:12]=1Komponenten
3
Versuchsvorschrift
Prepared according to the described general procedure 1 (GP1) by reaction of methyl 5-amino-5-(2,4-dimethoxypyridin-3-yl)pentanoate with 2-methylbenzo[d]thiazole-6-carbaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.63 min.; [M+H]+: 397.76 g/mol.
Aufarbeitung
- customPrepared
- customSubsequent purification by preparative HPLC