6-(Piperidin-1-yl)pyridine-2-carbaldehyde → HCID 69081625, Verbindung
Reaktionsgleichung
[NH2:1][CH:2]([C:9]1[C:14]([O:15][CH3:16])=[CH:13][CH:12]=[CH:11][C:10]=1[O:17][CH3:18])[CH2:3][CH2:4][C:5]([O:7]C)=O.[N:19]1([C:25]2[N:30]=[C:29]([CH:31]=O)[CH:28]=[CH:27][CH:26]=2)[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]1>>[CH3:18][O:17][C:10]1[CH:11]=[CH:12][CH:13]=[C:14]([O:15][CH3:16])[C:9]=1[CH:2]1[N:1]([CH2:31][C:29]2[CH:28]=[CH:27][CH:26]=[C:25]([N:19]3[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]3)[N:30]=2)[C:5](=[O:7])[CH2:4][CH2:3]1Komponenten
3
Versuchsvorschrift
Prepared according to the described general procedure 2 (GP2) by reaction of methyl 4-amino-4-(2,6-dimethoxyphenyl)butanoate with commercially available 6-(piperidin-1-yl)picolinaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.61 min.; [M+H]+: 396.00 g/mol.
Aufarbeitung
- customPrepared
- customSubsequent purification by preparative HPLC
- customafforded the target compound