HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Ethoxybenzaldehyde → 5-(2-Ethoxy-6-fluorophenyl)-1-(3-ethoxybenzyl)-3-methylpyrrolidin-2-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Ethoxybenzaldehyde | HCID 89908 | — |
| Edukt | Ethyl 4-amino-4-(2-ethoxy-6-fluorophenyl)-2-methylbutanoate | HCID 69083532 | — |
| Produkt | 5-(2-Ethoxy-6-fluorophenyl)-1-(3-ethoxybenzyl)-3-methylpyrrolidin-2-one | HCID 69084515 | — |
Reaktionsschritte
Prepared according to the described general procedure 2 (GP2) by reaction of ethyl 4-amino-4-(2-ethoxy-6-fluorophenyl)-2-methylbutanoate with commercially available 3-ethoxybenzaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.92 min.; [M+H]+: 372.03 g/mol.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09242970B2 |
| Quelldatensatz | uspto-grants-2016_01 |
| ORD ID | ord-8fa82841ee294f60b7591a6be06b96a0 |
| Quellennotiz | uspto-grants-2016_01 |