3-(2,2,2-Trifluoroethoxy)benzaldehyde → HCID 69082495, Verbindung

HRID 594740

Reaktionsgleichung

Reaktionsgleichung von HRID 594740
[NH2:1][CH:2]([C:11]1[C:16]([O:17][CH3:18])=[CH:15][CH:14]=[CH:13][C:12]=1[O:19][CH3:20])[CH2:3][CH:4]([CH3:10])[C:5]([O:7]CC)=O.[F:21][C:22]([F:34])([F:33])[CH2:23][O:24][C:25]1[CH:26]=[C:27]([CH:30]=[CH:31][CH:32]=1)[CH:28]=O>>[CH3:18][O:17][C:16]1[CH:15]=[CH:14][CH:13]=[C:12]([O:19][CH3:20])[C:11]=1[CH:2]1[N:1]([CH2:28][C:27]2[CH:30]=[CH:31][CH:32]=[C:25]([O:24][CH2:23][C:22]([F:21])([F:33])[F:34])[CH:26]=2)[C:5](=[O:7])[CH:4]([CH3:10])[CH2:3]1

Komponenten

3

Edukt 2

HCID 47709473-(2,2,2-Trifluoroethoxy)benzaldehydeHCID 69085588Ethyl 4-amino-4-(2,6-dimethoxyphenyl)-2-methylbutanoate

Produkt 1

HCID 69082495HCID 69082495, Verbindung

Versuchsvorschrift

Prepared according to the described general procedure 2 (GP2) by reaction of ethyl 4-amino-4-(2,6-dimethoxyphenyl)-2-methylbutanoate with 3-(2,2,2-trifluoroethoxy)benzaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.90 min.; [M+H]+: 424.43 g/mol.

Aufarbeitung

  1. customPrepared
  2. customSubsequent purification by preparative HPLC
  3. customafforded the target compound

Quellen und Nachweise

ORD-Eintrag
ord-8a91e520e0a3481f97315bf4378cf23e
Quelldatensatz
uspto-grants-2016_01
Patentnummer
US09242970B2

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