Hydrochloric Acid → HCID 68065988, Verbindung

HRID 594947Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 594947
C(O)C.[N:4]1[CH:5]=[CH:6][N:7]2[CH:12]=[C:11]([C:13]3[C:17]4[CH2:18][N:19](C(OC(C)(C)C)=O)[CH2:20][CH2:21][C:16]=4[NH:15][N:14]=3)[CH:10]=[CH:9][C:8]=12.Cl>O1CCOCC1>[N:4]1[CH:5]=[CH:6][N:7]2[CH:12]=[C:11]([C:13]3[C:17]4[CH2:18][NH:19][CH2:20][CH2:21][C:16]=4[NH:15][N:14]=3)[CH:10]=[CH:9][C:8]=12

Komponenten

5

Edukt 3

HCID 313Hydrochloric AcidHCID 702Ethanol2×HCID 68065989HCID 68065989, Verbindung

Produkt 1

HCID 68065988HCID 68065988, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 312751,4-DioxaneLösungsmittel

Versuchsvorschrift

In a flask, ethanol (1 mL) was added to tert-butyl 3-(imidazo[1,2-a]pyridin-6-yl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate (0.750 g, 0.0022 mol). Hydrochloric acid in dioxane (4 M, 8 mL) was added to the reaction and was stirred for 30 minutes. Ethanol (5 mL) was added to the reaction, and the resulting solution was concentrated in vacuo. The crude product was progressed to the next step without further purification.

Aufarbeitung

  1. concentrationthe resulting solution was concentrated in vacuo
  2. customThe crude product was progressed to the next step without further purification

Quellen und Nachweise

ORD-Eintrag
ord-e429da4b082344478720ab47bfa103fd
Quelldatensatz
uspto-grants-2016_01
Patentnummer
US09242981B2

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