Cyclobut A → 9-(2'-(Hydroxymethyl)-3'-methylcyclobutyl)adenine
Reaktionsgleichung
OCC1C(CO)CC1N1C=NC2C(=O)NC(N)=NC1=2.[OH:20][CH2:21][CH:22]1[CH:25]([CH2:26]O)[CH2:24][CH:23]1[N:28]1[CH:36]=[N:35][C:34]2[C:29]1=[N:30][CH:31]=[N:32][C:33]=2[NH2:37]>>[OH:20][CH2:21][CH:22]1[CH:25]([CH3:26])[CH2:24][CH:23]1[N:28]1[CH:36]=[N:35][C:34]2[C:29]1=[N:30][CH:31]=[N:32][C:33]=2[NH2:37]Komponenten
3
Versuchsvorschrift
Following the procedures described in Example 40, replacing 9-(2',3'-bis(hydroxymethyl)-cyclobutyl)guanine, the product of Example 1, with 9-(2',3'-bis(hydroxymethyl)cyclobutyl)adenine, Example 4, the title compound is prepared.
Quellen und Nachweise
- ORD-Eintrag
- ord-24435b4afdfa4eebb5264d51b0d621a6
- Quelldatensatz
- uspto-grants-1993_09
- Patentnummer
- US05246931
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