HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Aminoethyl sulfate → 2-(2-Hydroxy-4-phenylbutyl)aminoethyl hydrogen sulphate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Aminoethyl sulfate | HCID 70223 | — |
| Edukt | 2-(2-Phenylethyl)oxirane | HCID 135955 | — |
| Lösungsmittel | Methanol | HCID 887 | — |
| Lösungsmittel | Sodium Hydroxide | HCID 14798 | — |
| Produkt | 2-(2-Hydroxy-4-phenylbutyl)aminoethyl hydrogen sulphate | HCID 20354781 | — |
Reaktionsschritte
A mixture of 1,2-epoxy-4-phenylbutane (1.48 g.) and 2-aminoethyl hydrogen sulphate (7.05 g.) in methanol (7.5 ml.) and sodium hydroxide solution (18N, 2.8 ml.) is stirred at ambient temperature for 2 hours. The 2-(2-hydroxy-4-phenylbutyl)aminoethyl hydrogen sulphate formed as intermediate is not isolated but is cyclised in situ as follows:
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04010266 |
| Quelldatensatz | uspto-grants-1977_03 |
| ORD ID | ord-241d6d8f0f204c859c915f205a38dc50 |
| Quellennotiz | uspto-grants-1977_03 |