Dimethyl Sulfate → HCID 22452645, Verbindung

HRID 596590Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 596590
[OH:1][C:2]1[CH:3]=[C:4]([C:12]([OH:14])=[O:13])[C:5]2[CH2:6][CH2:7][CH2:8][CH2:9][C:10]=2[CH:11]=1.[OH-].[Na+].[CH3:17]OS(OC)(=O)=O>>[CH3:17][O:1][C:2]1[CH:3]=[C:4]([C:12]([OH:14])=[O:13])[C:5]2[CH2:6][CH2:7][CH2:8][CH2:9][C:10]=2[CH:11]=1

Komponenten

4

Edukt 3

HCID 6497Dimethyl SulfateHCID 14798Sodium HydroxideHCID 21450344HCID 21450344, Verbindung

Produkt 1

HCID 22452645HCID 22452645, Verbindung

Versuchsvorschrift

A mixture of 0.02 mole of 3-hydroxy-5,6,7,8-tetrahydronaphthalene-1-carboxylic acid, and 40 ml. of 2 N sodium hydroxide solution is treated with 0.04 mole of dimethylsulfate over a 5 minutes period, and the mixture is stirred for 24 hours. The mixture is washed with 3 × 50 ml. of ether and acidified with dilute hydrochloric acid. The precipitate is collected, washed with water, dried at room temperature and 100μ pressure and recrystallized from cyclohexane.

Aufarbeitung

  1. washThe mixture is washed with 3 × 50 ml
  2. customThe precipitate is collected
  3. washwashed with water
  4. customdried at room temperature
  5. custom100μ pressure and recrystallized from cyclohexane

Quellen und Nachweise

ORD-Eintrag
ord-be87bbe540cf4fb5b9c31419c109741a
Quelldatensatz
uspto-grants-1977_03
Patentnummer
US04011326

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