Pyridine → 1-Bromo-3,7,9-trimethyldeca-2,6-diene

19.8 g. of 3,7,9-trimethyl-1,6-decadien-3-ol, 100 ml. of hexane and 1 ml. of pyridine and cooled to -15° C. and treated dropwise over a period of 1.5 hours with a solution of 4 ml. of phosphorus tribromide in 50 ml. of hexane while maintaining the temperature between -15° and -10° C. The mixture is stirred for a further 90 minutes while slowly warming to room temperature. For the working-up, the mixture is poured on to 50 ml. of ice-water, the organic phase is separated and washed once with 20 ml. of 10% soda solution, once with 50 ml. of semi-saturated aqueous sodium chloride solution and once with 50 ml. saturated sodium chloride solution, dried over sodium sulphate and evaporated under reduced pressure. There is obtained 1-bromo-3,7,9-trimethyl-2,6-decadiene.

1. additiontreated dropwise over a period of 1.5 hours with a solution of 4 ml
2. additionthe mixture is poured on to 50 ml
3. customof ice-water, the organic phase is separated
4. washwashed once with 20 ml
5. dry with materialsaturated sodium chloride solution, dried over sodium sulphate
6. customevaporated under reduced pressure

ORD-Eintrag

ord-d4632101ccdb464f9dd9c1678292ae2e

Quelldatensatz

uspto-grants-1977_03

DOI

10.6084/m9.figshare.5104873.v1

Patentnummer

US04011335