Methyl isothiocyanate → Thiourea, N-(2,6-dichlorophenyl)-N'-methyl-

HRID 596650Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 596650
[Cl:1][C:2]1[CH:8]=[CH:7][CH:6]=[C:5]([Cl:9])[C:3]=1[NH2:4].[CH3:10][N:11]=[C:12]=[S:13]>C(O)C>[CH3:10][NH:11][C:12]([NH:4][C:3]1[C:2]([Cl:1])=[CH:8][CH:7]=[CH:6][C:5]=1[Cl:9])=[S:13]

Komponenten

4

Edukt 2

HCID 11167Methyl isothiocyanateHCID 118462,6-Dichloroaniline

Produkt 1

HCID 7942238Thiourea, N-(2,6-dichlorophenyl)-N'-methyl-

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

130 g of 2,6-dichloro-aniline, 100 g of methyl isothiocyanate and 300 ml of 95% ethanol are refluxed during 14 hours, with stirring. The resulting solution is cooled in the freezer: the white solid formed is filtered and washed with isopropyl oxide. After recrystallization from isopropanol, 65 g of product (III : R = CH3), m.p. = 184° C, are collected.

Aufarbeitung

  1. temperatureThe resulting solution is cooled in the freezer
  2. customthe white solid formed
  3. filtrationis filtered
  4. washwashed with isopropyl oxide
  5. customAfter recrystallization from isopropanol, 65 g of product (III : R = CH3), m.p. = 184° C
  6. customare collected

Quellen und Nachweise

ORD-Eintrag
ord-3971929cc6e24d77b53f34cdb3ed7ad5
Quelldatensatz
uspto-grants-1977_03
Patentnummer
US04011342

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