2-Benzyl-2-methyl-5-hydroxy-6,7-dichloro-1-indanone → 2-Benzyl-2-methyl-6,7-dichloro-1,5-indandiol
Reaktionsgleichung
[CH2:1]([C:8]1([CH3:21])[CH2:16][C:15]2[C:10](=[C:11]([Cl:19])[C:12]([Cl:18])=[C:13]([OH:17])[CH:14]=2)[C:9]1=[O:20])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[H-].COCCO[Al+]OCCOC.[Na+].[H-]>O1CCCC1>[CH2:1]([C:8]1([CH3:21])[CH2:16][C:15]2[C:10](=[C:11]([Cl:19])[C:12]([Cl:18])=[C:13]([OH:17])[CH:14]=2)[CH:9]1[OH:20])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
2-Benzyl-2-methyl-6,7-dichloro-1,5-indandiol is prepared following substantially the same procedure described in Example 4, Step E, using the following substances: 2-benzyl-2-methyl-5-hydroxy-6,7-dichloro-1-indanone (4.8 g., 0.015 mole); sodium bis-(2-methoxyethoxy)-aluminum hydride (70% in benzene [5 ml.]); and tetrahydrofuran (50 ml.).