3-Amino-N-methylbenzamide → 4-chloro-3-(trifluoromethyl)phenyl-N'-(4-(3-methylcarbamoylphenyl)carbamoylphenyl) urea

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	3-Amino-N-methylbenzamide	HCID 676526	—
Edukt	4-Chloro-3-(trifluoromethyl)phenyl-N'-(4-carboxyphenyl)urea	HCID 23614596	—
Produkt	4-chloro-3-(trifluoromethyl)phenyl-N'-(4-(3-methylcarbamoylphenyl)carbamoylphenyl) urea	HCID 23614591	—

Reaktionsschritte

Entry 67: N-(4-Chloro-3-(trifluoromethyl)phenyl-N′-(4-ethoxycarbonylphenyl) urea was synthesized according to Method C1e. N-(4-Chloro-3-(trifluoromethyl)phenyl-N′-(4-ethoxycarbonylphenyl) urea was saponified according to Method D3 to give N-(4-chloro-3-(trifluoromethyl)phenyl-N-(4-carboxyphenyl) urea. N-(4-Chloro-3-(trifluoromethyl)phenyl-N′-(4-carboxyphenyl) urea was coupled with 3-methylcarbamoylaniline according to Method D1b to give N-(4-chloro-3-(trifluoromethyl)phenyl-N′-(4-(3-methylcarbamoylphenyl)carbamoylphenyl) urea.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07897623B2
Quelldatensatz	uspto-grants-2011_03
ORD ID	ord-0fdfbdd527804051954cf8686bb5cc9e
Quellennotiz	uspto-grants-2011_03