HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Benzofuran → (RS)-2-(1-Benzofuran-2-yl-methanoyl)-4-methyl-piperazine-1-carboxylic acid tert-butyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Benzofuran | HCID 9223 | — |
| Edukt | (RS)-2-(methoxy-methyl-carbamoyl)4-methyl-piperazine-1-carboxylic acid dimethyl-ethyl ester | HCID 86625772 | — |
| Produkt | (RS)-2-(1-Benzofuran-2-yl-methanoyl)-4-methyl-piperazine-1-carboxylic acid tert-butyl ester | HCID 66968186 | 52% |
Reaktionsschritte
The title compound (1.81 g, 52%) was prepared from (RS)-2-(methoxy-methyl-carbamoyl)-4-methyl-piperazine-1-carboxylic acid dimethyl-ethyl ester, D54 (2.9 g, 10.1 mmol) and benzofuran (0.74 g, 10.1 mol) using the method of Description 2.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07897618B2 |
| Quelldatensatz | uspto-grants-2011_03 |
| ORD ID | ord-f6e7a548cb1f45b6ab5e8cefcf7a9380 |
| Quellennotiz | uspto-grants-2011_03 |