HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Guaiacol → 1-(2-Methoxyphenoxy)-2-nitrobenzene
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Guaiacol | HCID 460 | — |
| Edukt | 2-Aminothiazole | HCID 2155 | — |
| Edukt | 1-Fluoro-2-nitrobenzene | HCID 73895 | — |
| Edukt | 2-(2-Methoxyphenoxy)aniline | HCID 254144 | — |
| Produkt | 1-(2-Methoxyphenoxy)-2-nitrobenzene | HCID 254143 | 81% |
Reaktionsschritte
2-(2-Methoxyphenoxy)-1-nitrobenzene (0.99 g, 81%) was prepared from 2-methoxy-phenol (0.68 g, 5.5 mmol) and 1-fluoro-2-nitrobenzene (0.71 g, 5.0 mmol) following the general procedure A. This was reduced to 2-(2-methoxyphenoxy)aniline (0.63 g, 73%) following general procedure B. N-2-(2-Methoxyphenoxy)phenyl-N′-(thiazol-2-yl)urea (110 g, 65%) was prepared from 2-(2-methoxyphenoxy)aniline (108 mg, 0.5 mmol) and 2-amino-thiazole (60 mg, 0.6 mmol) following the general procedure D.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07897628B2 |
| Quelldatensatz | uspto-grants-2011_03 |
| ORD ID | ord-963779e8d79340f08df2c397b0bf8c6d |
| Quellennotiz | uspto-grants-2011_03 |