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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 600788Erstellt: 25. Oktober 2026

8-{5-[4-(Trifluoromethyl)phenyl]oxazol-2-ylamino}-3,4-dihydronaphthalen-2(1H)-one → 8-[(5-Phenyl-1,3-oxazol-2-yl)amino]-1,2,3,4-tetrahydronaphthalen-2-ol

https://huagongshe.com/reaction/600788

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt8-{5-[4-(Trifluoromethyl)phenyl]oxazol-2-ylamino}-3,4-dihydronaphthalen-2(1H)-oneHCID 11955840—
Edukt8-[(5-phenyl-1,3-oxazol-2-yl)amino]-3,4-dihydronaphthalen-2(1H)-oneHCID 11964237—
Produkt8-[(5-Phenyl-1,3-oxazol-2-yl)amino]-1,2,3,4-tetrahydronaphthalen-2-olHCID 11964283—

Reaktionsschritte

The title compound was prepared using the procedure as described in Example 2, substituting the product of Example 11C for the product of Example 1I. 1H NMR (DMSO-d6) 9.11 (s, 1H), 7.59 (m, 3H), 7.41 (t, 2H, J=7.7 Hz), 7.37 (s, 1H), 7.25 (t, 1H, J=7.5 Hz), 7.09 (t, 1H, J=7.5 Hz), 6.84 (d, 1H, J=7.1 Hz), 4.80 (d, 1H, J=4.1 Hz), 3.93 (m, 1H), 2.73-2.99 (m, 4H), 1.86 (m, 1H), 1.62 (m, 1H); MS (ESI+) m/z 307 (M+H).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07902236B2
Quelldatensatzuspto-grants-2011_03
ORD IDord-29cb678f4eb84b788bfcc2781bdaa201
Quellennotizuspto-grants-2011_03