HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Thionyl Chloride → 3-Methoxy-4-(2-propynyloxy)benzoyl chloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Thionyl Chloride | HCID 24386 | — |
| Edukt | 3-Methoxy-4-(prop-2-ynyloxy)benzoic acid | HCID 13121480 | — |
| Katalysator | Dimethylformamide | HCID 6228 | — |
| Lösungsmittel | Toluene | HCID 1140 | — |
| Produkt | 3-Methoxy-4-(2-propynyloxy)benzoyl chloride | HCID 57445671 | 84,1% |
Reaktionsschritte
To 100 ml of toluene were added 12.0 g of 4-(2-propynyloxy)-3-methoxybenzoic acid, 9.0 g of thionyl chloride and 50 mg of DMF, and the mixture obtained was heated under reflux for 3 hours. Then, the reaction mixture was concentrated. The solid obtained was washed with hexane to obtain 11.0 g of 4-(2-propynyloxy)-3-methoxybenzoyl chloride represented by the formula.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07902400B2 |
| Quelldatensatz | uspto-grants-2011_03 |
| ORD ID | ord-c4844b0198954552a6ae17f7c6d001e8 |
| Quellennotiz | uspto-grants-2011_03 |