3-Amino-4-(4-methoxy-phenylsulfanyl)-benzoic acid methyl ester → 4-(4-Methoxy-phenylsulfanyl)-3-(pyrido[2,3-d]pyrimidin-4-ylamino)-benzoic acid methyl ester

HRID 605280Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 605280
[CH3:1][O:2][C:3](=[O:20])[C:4]1[CH:9]=[CH:8][C:7]([S:10][C:11]2[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][CH:12]=2)=[C:6]([NH2:19])[CH:5]=1.C([C:23]1[C:24]([N:29]=[CH:30][N:31]([CH3:33])C)=[N:25][CH:26]=[CH:27][CH:28]=1)#N>>[CH3:1][O:2][C:3](=[O:20])[C:4]1[CH:9]=[CH:8][C:7]([S:10][C:11]2[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][CH:12]=2)=[C:6]([NH:19][C:33]2[C:23]3[CH:28]=[CH:27][CH:26]=[N:25][C:24]=3[N:29]=[CH:30][N:31]=2)[CH:5]=1

Komponenten

3

Edukt 2

HCID 613055833-Amino-4-(4-methoxy-phenylsulfanyl)-benzoic acid methyl esterHCID 66808319N'-(3-Cyano-pyridin-2-yl)-N,N-dimethyl-formamidine2×

Produkt 1

HCID 670406454-(4-Methoxy-phenylsulfanyl)-3-(pyrido[2,3-d]pyrimidin-4-ylamino)-benzoic acid methyl ester

Versuchsvorschrift

The product from Example 136B and the product from Example 29A were reacted according to the procedure from Example 136C substituting the product from Example 29A for the product from Example 8E to provide the title compound.

Quellen und Nachweise

ORD-Eintrag
ord-63966feeb0d145779c953a9d7fbbe186
Quelldatensatz
uspto-grants-2011_03
Patentnummer
US07910595B2

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