N-[5-(4-Hydroxy-phenylsulfanyl)-2-methyl-4-nitro-phenyl]-benzamide → N-[4-Amino-5-(4-hydroxy-phenylsulfanyl)-2-methyl-phenyl]-benzamide

HRID 605293Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 605293
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:9]2[C:10]([N+:25]([O-])=O)=[CH:11][C:12]([CH3:24])=[C:13]([NH:15][C:16](=[O:23])[C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[CH:14]=2)=[CH:4][CH:3]=1.OC1C=CC(SC2C([N+]([O-])=O)=CC(C)=C(NC(=O)CC3C=CC=CC=3)C=2)=CC=1>>[NH2:25][C:10]1[C:9]([S:8][C:5]2[CH:6]=[CH:7][C:2]([OH:1])=[CH:3][CH:4]=2)=[CH:14][C:13]([NH:15][C:16](=[O:23])[C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[C:12]([CH3:24])[CH:11]=1

Komponenten

3

Edukt 2

HCID 67040761N-[5-(4-Hydroxy-phenylsulfanyl)-2-methyl-4-nitro-phenyl]-benzamide2×HCID 67041085N-[5-(4-Hydroxy-phenylsulfanyl)-2-methyl-4-nitro-phenyl]-2-phenyl-acetamide

Produkt 1

HCID 67040289N-[4-Amino-5-(4-hydroxy-phenylsulfanyl)-2-methyl-phenyl]-benzamideAusbeute 100 %

Versuchsvorschrift

The product from Example 267B was reacted according to the procedure from Example 265C substituting the product from Example 267B for the product from Example 265B to provide the title compound as a brown solid (0.11 g, 100%). This material was utilized without purification by silica gel chromatography.

Quellen und Nachweise

ORD-Eintrag
ord-bb73e60440204624b03b795b13312e09
Quelldatensatz
uspto-grants-2011_03
Patentnummer
US07910595B2

Notizen zur Reaktion

Wird geladen…