Triphenylphosphine → (3-Cyanobenzyl)triphenylphosphonium bromide

HRID 605789Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 605789
[C:1]1([P:7]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:20]([C:22]1[CH:23]=[C:24]([CH:27]=[CH:28][CH:29]=1)[CH2:25][Br:26])#[N:21]>>[Br-:26].[C:20]([C:22]1[CH:23]=[C:24]([CH:27]=[CH:28][CH:29]=1)[CH2:25][P+:7]([C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1)#[N:21]

Komponenten

3

Edukt 2

HCID 11776TriphenylphosphineHCID 97249Benzonitrile, 3-(bromomethyl)-

Produkt 1

HCID 2778355(3-Cyanobenzyl)triphenylphosphonium bromideAusbeute 72,7 %

Reaktionsbedingungen

Temperatur
80 °C

Versuchsvorschrift

Triphenylphosphine (2.8 g) was added to a Tol (50 ml) solution of 3-cyanobenzyl bromide (2.0 g), followed by stirring at 80° C. for 5 hours. This was cooled to room temperature, and the precipitated solid was collected by filtration, and washed with Tol. This was dried under reduced pressure to obtain (3-cyanobenzyl)(triphenyl)phosphonium bromide (3.4 g).

Aufarbeitung

  1. temperatureThis was cooled to room temperature
  2. filtrationthe precipitated solid was collected by filtration
  3. washwashed with Tol
  4. customThis was dried under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-5ee4e84298684cc38906189079ebdf4a
Quelldatensatz
uspto-grants-2011_03
Patentnummer
US07915261B2

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