Sulfuric Acid → 2-Amino-5-nitrobenzamide

Reaktionsgleichung

[NH2:1][C:2]1[CH:9]=[CH:8][C:7]([N+:10]([O-:12])=[O:11])=[CH:6][C:3]=1[C:4]#[N:5].S(=O)(=O)(O)[OH:14]>>[NH2:1][C:2]1[CH:9]=[CH:8][C:7]([N+:10]([O-:12])=[O:11])=[CH:6][C:3]=1[C:4]([NH2:5])=[O:14]

Komponenten

Edukt 2

HCID 1118Sulfuric Acid

HCID 285322-Amino-5-nitrobenzonitrile

Produkt 1

HCID 976652-Amino-5-nitrobenzamide

Reaktionsbedingungen

Temperatur: 130 °C

Versuchsvorschrift

A mixture of 2-amino-5-nitrobenzonitrile (25.4 g) and sulfuric acid (70 mL) was stirred at 130° C. for 40 min. The reaction mixture was added slowly to ice water, and the precipitate was collected by filtration, washed with water, ethanol and diethyl ether to give 2-amino-5-nitrobenzamide (24.6 g).

Aufarbeitung

filtrationthe precipitate was collected by filtration
washwashed with water, ethanol and diethyl ether

Quellen und Nachweise

ORD-Eintrag: ord-81a291086d23419792bc4437853ea22c
Quelldatensatz: uspto-grants-2011_03
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US07915267B2

Notizen zur Reaktion

Wird geladen…