HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Benzylamine → (3S,4S,6R)-6-benzhydryl-4-benzylamino-tetrahydropyran-3-ol
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Benzylamine | HCID 7504 | — |
| Edukt | (1S,4R,6R)-4-benzhydryl-3,7-dioxa-bicyclo[4.1.0]-heptane | HCID 86605348 | — |
| Produkt | (3S,4S,6R)-6-benzhydryl-4-benzylamino-tetrahydropyran-3-ol | HCID 66632020 | — |
Reaktionsschritte
(1S, 4R, 6R)-4-benzhydryl-3,7-dioxa-bicyclo[4.1.0]heptane 28d (0.019 g, 0.071 mmol) was reacted with benzylamine (0.15 g, 1.43 mmol) (Procedure E) to yield (3S, 4S, 6R)-6-benzhydryl-4-benzylamino-tetrahydropyran-3-ol, (+)-29 h, 0.023 (85%, [α]D=(+)70.1, c=1, MeOH).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07915433B2 |
| Quelldatensatz | uspto-grants-2011_03 |
| ORD ID | ord-81d2acb4121a4021b5a2919960047501 |
| Quellennotiz | uspto-grants-2011_03 |