Dimethylformamide dimethyl acetal → N'-(2-Benzylsulfanyl-5-cyano-pyrimidin-4-yl)-N,N-dimethyl-formamidine

HRID 607276Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 607276
[NH2:1][C:2]1[C:7]([C:8]#[N:9])=[CH:6][N:5]=[C:4]([S:10][CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[N:3]=1.CO[CH:20](OC)[N:21]([CH3:23])[CH3:22].C(C1C(N=CN(C)C)=NC(SCC)=NC=1)#N>>[CH2:11]([S:10][C:4]1[N:3]=[C:2]([N:1]=[CH:20][N:21]([CH3:23])[CH3:22])[C:7]([C:8]#[N:9])=[CH:6][N:5]=1)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Komponenten

4

Edukt 3

HCID 78373Dimethylformamide dimethyl acetalHCID 2958834-Amino-2-benzylsulfanylpyrimidine-5-carbonitrile2×HCID 66808651N'-(5-Cyano-2-ethylsulfanyl-pyrimidin-4-yl)-N,N-dimethyl-formamidine

Produkt 1

HCID 66808495N'-(2-Benzylsulfanyl-5-cyano-pyrimidin-4-yl)-N,N-dimethyl-formamidine

Versuchsvorschrift

A solution of the product from Example 183B was reacted with N,N-dimethylformamide dimethyl acetal according to the procedure from Example 156B substituting the product from Example 183B for the product from Example 156B to provide the title compound.

Quellen und Nachweise

ORD-Eintrag
ord-ac9ce5a1c2e94b61946f4741f1e1ebbb
Quelldatensatz
uspto-grants-2011_03
Patentnummer
US07915411B2

Notizen zur Reaktion

Wird geladen…